Title : Paroxetine modulates immune responses by activating a JAK2/STAT3 signaling pathway.

Pub. Date : 2020 May

PMID : 32020710






1 Functional Relationships(s)
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1 Our results indicated that paroxetine attenuates proinflammatory cytokine production (interleukin-1beta [IL-1beta], IL-17, and tumor necrosis factor-alpha) and increases expression of IL-10 and JAK2/STAT3 evidence for macrophages polarization to M2 subset and functional dendritic cells depletion. Paroxetine interleukin 1 alpha Homo sapiens