Pub. Date : 2020 Feb 4
PMID : 32009527
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Methods and Results The effects of ASA on CD40L-treated human platelets, in response to suboptimal concentrations of collagen or thrombin, were assessed at levels of aggregation, thromboxane A2 secretion, and phosphorylation of p38 mitogen-activated protein kinase, nuclear factor kappa B, transforming growth factor-beta-activated kinase 1, and myosin light chain. | Aspirin | coagulation factor II, thrombin | Homo sapiens |
| 2 | sCD40L significantly elevated thromboxane A2 secretion in platelets in response to suboptimal doses of collagen and thrombin, which was reversed by ASA. | Aspirin | coagulation factor II, thrombin | Homo sapiens |
| 3 | sCD40L potentiated platelet aggregation, an effect completely reversed and partially reduced by ASA in response to a suboptimal dose of collagen and thrombin, respectively. | Aspirin | coagulation factor II, thrombin | Homo sapiens |