Title : Anethole compromises human sperm function by affecting the sperm intracellular calcium concentration and tyrosine phosphorylation.

Pub. Date : 2020 Apr

PMID : 32004625






2 Functional Relationships(s)
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1 The results indicated that 10 and 100 muM anethole significantly reduced the motility, hyperactivation, and penetration ability of human sperm (P < 0.05) and inhibited the increase in human sperm functions induced by progesterone, a hormone essential for sperm function activation. Progesterone latexin Homo sapiens
2 Additionally, 10 and 100 muM anethole decreased both basal and progesterone-increased tyrosine phosphorylation, [Ca2+]i, and the current of CATSPER, a cation channel of sperm predominant for Ca2+ influx. Progesterone latexin Homo sapiens