Title : Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies.

Pub. Date : 2020 Mar 30

PMID : 32001245






2 Functional Relationships(s)
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1 Hydroxylation activity at the 6beta-position of steroid hormones (testosterone, progesterone, and cortisol) by human cytochromes P450 (CYP) 3A4, polymorphic CYP3A5, and fetal CYP3A7 were compared to understand the catalytic properties of the major forms of human CYP3A subfamily. Hydrocortisone cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Testosterone, progesterone, and cortisol 6beta-hydroxylation activities of recombinant CYP3A4, CYP3A5, and CYP3A7 were determined by liquid chromatography. Hydrocortisone cytochrome P450 family 3 subfamily A member 4 Homo sapiens