Title : Selective inhibitors for JNK signalling: a potential targeted therapy in cancer.

Pub. Date : 2020 Dec

PMID : 31994958






2 Functional Relationships(s)
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1 Some ATP-competitive inhibitors of JNK, such as SP600125 and AS601245, are widely used in vitro; however, this type of inhibitor lacks specificity as they indiscriminately inhibit phosphorylation of all JNK substrates. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens
2 Some ATP-competitive inhibitors of JNK, such as SP600125 and AS601245, are widely used in vitro; however, this type of inhibitor lacks specificity as they indiscriminately inhibit phosphorylation of all JNK substrates. Adenosine Triphosphate mitogen-activated protein kinase 8 Homo sapiens