Pub. Date : 2020 Mar
PMID : 31985018
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The western blot analysis data suggested that ICI 182780, which causes estrogen receptor alpha (ERalpha) degradation, reversed the icaritin-induced decrease in SOST expression, which was inconsistent with the results of immunofluorescence analysis. | icaritin | estrogen receptor 1 | Homo sapiens |
2 | The western blot analysis data suggested that ICI 182780, which causes estrogen receptor alpha (ERalpha) degradation, reversed the icaritin-induced decrease in SOST expression, which was inconsistent with the results of immunofluorescence analysis. | icaritin | estrogen receptor 1 | Homo sapiens |
3 | In conclusion, icaritin was demonstrated to promote the osteogenesis of hBMSCs by downregulating SOST expression, and icaritin-induced suppression of SOST was regulated in part via the Wnt/beta-catenin/ERalpha axis. | icaritin | estrogen receptor 1 | Homo sapiens |