Pub. Date : 2020 May
PMID : 31972238
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We also studied mice with homozygous disruption of ApoE (ApoE-/- mice), which spontaneously develop high serum cholesterol. | Cholesterol | apolipoprotein E | Mus musculus |
| 2 | We also studied mice with homozygous disruption of ApoE (ApoE-/- mice), which spontaneously develop high serum cholesterol. | Cholesterol | apolipoprotein E | Mus musculus |
| 3 | RESULTS: C57BL/6J mice on HCD and ApoE-/- mice with high serum levels of cholesterol developed fewer and smaller liver tumors and lung metastases after diethylinitrosamine injection or implantation of Hep1-6 cells than mice on ND. | Cholesterol | apolipoprotein E | Mus musculus |
| 4 | CONCLUSIONS: Mice with increased serum levels of cholesterol due to an HCD or genetic disruption of ApoE develop fewer and smaller tumors after injection of hepatoma cells or a chemical carcinogen. | Cholesterol | apolipoprotein E | Mus musculus |