Title : The endoplasmic reticulum stress and related signal pathway mediated the glyphosate-induced testosterone synthesis inhibition in TM3 cells.

Pub. Date : 2020 May

PMID : 31968290






1 Functional Relationships(s)
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1 Treatment TM3 cells with glyphosate at 5 mg/L not only reduced the protein levels of testosterone synthase StAR and CYP17A1, inhibited testosterone secretion, but also increased the protein level of ER stress molecule Bip and promoted the phosphorylation of PERK and eIF2alpha. Testosterone steroidogenic acute regulatory protein Mus musculus