Title : Organocatalyzed Solvent Free and Efficient Synthesis of 2,4,5-Trisubstituted Imidazoles as Potential Acetylcholinesterase Inhibitors for Alzheimer's Disease.

Pub. Date : 2020 Mar

PMID : 31968151






1 Functional Relationships(s)
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1 Among this series of compounds 3m bearing one ethoxy and a hydroxyl group on the phenyl ring on 2,4,5-trisubstituted imidazoles proved potent AChE inhibitor (102.56+-0.14). Hydroxyl Radical acetylcholinesterase (Cartwright blood group) Homo sapiens