Title : The Effects of TiO2 Nanoparticles on Cisplatin Cytotoxicity in Cancer Cell Lines.

Pub. Date : 2020 Jan 17

PMID : 31963452






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TiO2 PEG NPs may affect P-glycoprotein (P-gp), a membrane efflux channel involved in MDR. Polyethylene Glycols ATP binding cassette subfamily B member 1 Homo sapiens
2 TiO2 PEG NPs may affect P-glycoprotein (P-gp), a membrane efflux channel involved in MDR. Polyethylene Glycols ATP binding cassette subfamily B member 1 Homo sapiens
3 TiO2 PEG NPs treatment decreased the expression level of P-gp in HepG2 cells. Polyethylene Glycols ATP binding cassette subfamily B member 1 Homo sapiens
4 Our findings indicate that TiO2 PEG NPs enhance cisplatin cytotoxicity by down regulating P-gp and that TiO2 PEG NPs are promising candidates for inhibiting P-gp and reversing drug resistance acquired by cancer cells. Polyethylene Glycols ATP binding cassette subfamily B member 1 Homo sapiens