Pub. Date : 2020 Jan 20
PMID : 31959784
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Considerable data support a role for hypochlorous acid (HOCl), generated by the leukocyte-derived heme-protein myeloperoxidase (MPO) in these changes. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 2 | Considerable data support a role for hypochlorous acid (HOCl), generated by the leukocyte-derived heme-protein myeloperoxidase (MPO) in these changes. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 3 | Considerable data support a role for hypochlorous acid (HOCl), generated by the leukocyte-derived heme-protein myeloperoxidase (MPO) in these changes. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 4 | Considerable data support a role for hypochlorous acid (HOCl), generated by the leukocyte-derived heme-protein myeloperoxidase (MPO) in these changes. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 5 | MPO is shown to co-localize with matrix fibronectin as detected by confocal microscopy, and bound active MPO can initiate ECM modification, as detected by decreased antibody recognition of fibronectin, versican and type IV collagen, and formation of protein carbonyls and HOCl-mediated damage. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 6 | MPO is shown to co-localize with matrix fibronectin as detected by confocal microscopy, and bound active MPO can initiate ECM modification, as detected by decreased antibody recognition of fibronectin, versican and type IV collagen, and formation of protein carbonyls and HOCl-mediated damage. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 7 | HOCl-induced modifications enhance MPO binding to ECM proteins as detected by ELISA and MPO activity measurements. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 8 | HOCl-induced modifications enhance MPO binding to ECM proteins as detected by ELISA and MPO activity measurements. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 9 | These data demonstrate that MPO-generated HOCl induces ECM modification by interacting with ECM proteins in a site-specific manner, and generates alterations that increase MPO adhesion. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |
| 10 | These data demonstrate that MPO-generated HOCl induces ECM modification by interacting with ECM proteins in a site-specific manner, and generates alterations that increase MPO adhesion. | Hypochlorous Acid | myeloperoxidase | Homo sapiens |