Title : Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress.

Pub. Date : 2020 Jul

PMID : 31925927






1 Functional Relationships(s)
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1 RESULTS: Nicotine inhibits the increase in TXNIP and the decrease in Insulin 1/proinsulin expression levels induced by either forced IRE1alpha hyperactivation or ER stress agents. Nicotine insulin Homo sapiens