Title : Luteolin reduces fat storage in Caenorhabditis elegans by promoting the central serotonin pathway.

Pub. Date : 2020 Jan 29

PMID : 31912839






2 Functional Relationships(s)
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1 In wild-type N2 worms, luteolin treatment not only elevated the expression of tph-1, but also enhanced the mRNA levels of mod-1 and ser-6, which are two serotonin-related receptors and play specific roles in serotonin-mediated fat reduction. Luteolin Uncharacterized protein Caenorhabditis elegans
2 The mutation of either mod-1 or ser-6 also fully abolished luteolin-induced fat loss. Luteolin Uncharacterized protein Caenorhabditis elegans