Title : Mitochondrial localization of Dictyostelium discoideum dUTPase mediated by its N-terminus.

Pub. Date : 2020 Jan 7

PMID : 31910901






2 Functional Relationships(s)
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1 To begin to investigate how the pyrimidine biosynthetic pathway fulfills the demand for dTTP, we determined the catalytic properties and structure of the key enzyme deoxyuridine triphosphate nucleotidohydrolase (dUTPase) that hydrolyzes dUTP to dUMP, the precursor of dTTP. thymidine 5'-triphosphate Deoxyuridine triphosphatase Drosophila melanogaster
2 To begin to investigate how the pyrimidine biosynthetic pathway fulfills the demand for dTTP, we determined the catalytic properties and structure of the key enzyme deoxyuridine triphosphate nucleotidohydrolase (dUTPase) that hydrolyzes dUTP to dUMP, the precursor of dTTP. thymidine 5'-triphosphate Deoxyuridine triphosphatase Drosophila melanogaster