Pub. Date : 1988 Oct 15
PMID : 3190739
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Structural specificity of inhibition of human folylpolyglutamate synthetase by ornithine-containing folate analogs. | Folic Acid | folylpolyglutamate synthase | Homo sapiens |
| 2 | A series of folate analogs containing ornithine instead of glutamate was synthesized and tested for inhibition of folylpolyglutamate synthetase (FPGS) and other folate-dependent enzymes of human leukemia cell lines. | Folic Acid | folylpolyglutamate synthase | Homo sapiens |
| 3 | A series of folate analogs containing ornithine instead of glutamate was synthesized and tested for inhibition of folylpolyglutamate synthetase (FPGS) and other folate-dependent enzymes of human leukemia cell lines. | Folic Acid | folylpolyglutamate synthase | Homo sapiens |
| 4 | Because of the lack of appreciable interaction with other folate-dependent enzymes, structures incorporating the 2-amino-4-oxo-5,8-dideazapteroate nucleus may thus lead to selective inhibition of FPGS. | Folic Acid | folylpolyglutamate synthase | Homo sapiens |