Title : Cardiac-Specific Overexpression of Catalytically Inactive Corin Reduces Edema, Contractile Dysfunction, and Death in Mice with Dilated Cardiomyopathy.

Pub. Date : 2019 Dec 27

PMID : 31892216






1 Functional Relationships(s)
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1 Humans with dilated cardiomyopathy (DCM) and heart failure (HF) develop low levels of corin, a multi-domain, cardiac-selective serine protease involved in natriuretic peptide cleavage and sodium and water regulation. cholecystokinin C-terminal flanking peptide corin, serine peptidase Mus musculus