Pub. Date : 2020 Jan
PMID : 31864171
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A recently characterized CD-1 mouse model of phenobarbital (PB)-resistant neonatal ischemic-seizures (i.e.; unilateral carotid ligation) was shown to be associated with age-dependent (P7 vs. P10) acute seizure severity and PB-efficacy (i.e.; PB-resistant vs. PB-responsive). | Phenobarbital | S100 calcium binding protein A10 (calpactin) | Mus musculus |
| 2 | A recently characterized CD-1 mouse model of phenobarbital (PB)-resistant neonatal ischemic-seizures (i.e.; unilateral carotid ligation) was shown to be associated with age-dependent (P7 vs. P10) acute seizure severity and PB-efficacy (i.e.; PB-resistant vs. PB-responsive). | Phenobarbital | S100 calcium binding protein A10 (calpactin) | Mus musculus |
| 3 | ANA12 + PB treatment, but not PB-alone, rescued the loss of gamma power homeostasis present in P7 ligate-control but absent in P10 ligate group, highlighting the age-dependence. | Phenobarbital | S100 calcium binding protein A10 (calpactin) | Mus musculus |
| 4 | In contrast, PB-alone treatment, but not ANA12+PB, significantly reduced the elevated delta-AUC observed in P10 ligate-controls, when PB is efficacious by itself. | Phenobarbital | S100 calcium binding protein A10 (calpactin) | Mus musculus |