Title : Novel inter-domain Ca2+-binding site in the gelsolin superfamily protein fragmin.

Pub. Date : 2020 Mar

PMID : 31863323






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Novel inter-domain Ca2+-binding site in the gelsolin superfamily protein fragmin. Calcium gelsolin Homo sapiens
2 Gelsolin superfamily proteins, consisting of multiple domains (usually six), sever actin filaments and cap the barbed ends in a Ca2+-dependent manner. Calcium gelsolin Homo sapiens
3 Two types of evolutionally conserved Ca2+-binding sites have been identified in this family; type-1 (between gelsolin and actin) and type-2 (within the gelsolin domain). Calcium gelsolin Homo sapiens
4 Two types of evolutionally conserved Ca2+-binding sites have been identified in this family; type-1 (between gelsolin and actin) and type-2 (within the gelsolin domain). Calcium gelsolin Homo sapiens
5 Our results provide the first structural evidence for the existence of an unconventional Ca2+-binding site in the gelsolin superfamily proteins. Calcium gelsolin Homo sapiens