Title : Subcutaneous administration of β-hydroxybutyrate improves learning and memory of sepsis surviving mice.

Pub. Date : 2020 Apr

PMID : 31853744






1 Functional Relationships(s)
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1 In the coculture of neurons, astrocytes, and BV2 cells (a microglial cell line), knocking down the expression of microglial HCA2 (BHB receptor) via a specific shRNA reduced the protection of BHB to lipopolysaccharide-induced inflammatory response and neuron damage more significantly than knocking down neuronal MCT2 (BHB transporter). 3-Hydroxybutyric Acid solute carrier family 16 (monocarboxylic acid transporters), member 7 Mus musculus