Pub. Date : 2020 Feb 20
PMID : 31846764
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Global characterization of proteome and lysine methylome features in EZH2 wild-type and mutant lymphoma cell lines. | tyrosyl-lysine | enhancer of zeste 2 polycomb repressive complex 2 subunit | Homo sapiens |
| 2 | EZH2, a methyltransferase specifically trimethylates the lysine 27 of histone H3 and its aberrance in several cancers promotes the development of its inhibitors against hematological tumors. | tyrosyl-lysine | enhancer of zeste 2 polycomb repressive complex 2 subunit | Homo sapiens |
| 3 | In this study, we presented a deep exploration of lysine mono-, di- and trimethylomes in EZH2 wild-type and Y641 mutant lymphoma cell lines. | tyrosyl-lysine | enhancer of zeste 2 polycomb repressive complex 2 subunit | Homo sapiens |
| 4 | SIGNIFICANCE: Our study showed the global landscape of mono-, di- and trimethylomes in the EZH2-aberrant DLBCL cell lines, revealing the molecular characteristics of lysine methylation. | tyrosyl-lysine | enhancer of zeste 2 polycomb repressive complex 2 subunit | Homo sapiens |