Pub. Date : 2020 Mar
PMID : 31846433
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In papillary (B-CPAP ) and anaplastic (8505c) cell lines, mebendazole increased the percentage cells in G2/M cell cycle arrest and induced late stage apoptosis by activation of the caspase-3 pathway. | Mebendazole | centromere protein J | Homo sapiens |
| 2 | In vivo, mebendazole treatment resulted in significant orthotopic thyroid tumor regression (B-CPAP) and growth arrest (8505c), with treated tumors displaying reduced expression of the proliferation maker Ki67 and less vascular epithelium as indicated by CD31+ immunohistochemistry. | Mebendazole | centromere protein J | Homo sapiens |