Title : Proteolytic processing of PD-L1 by ADAM proteases in breast cancer cells.

Pub. Date : 2020 Jan

PMID : 31796994






1 Functional Relationships(s)
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1 Notably, treatment of cells with ionomycin, a calcium ionophore and a known activator of ADAM10, or with phorbol 12-myristate 13-acetate, an activator of ADAM17, dramatically increases the release of soluble PD-L1 to the media. Ionomycin ADAM metallopeptidase domain 10 Homo sapiens