Title : PNPLA3 I148M mediates the regulatory effect of NF-kB on inflammation in PA-treated HepG2 cells.

Pub. Date : 2020 Jan

PMID : 31793207






2 Functional Relationships(s)
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1 The silencing of PNPLA3 blocked the overexpression of NF-kB or PA-induced TNF-alpha up-regulation. Palmitic Acid tumor necrosis factor Homo sapiens
2 Moreover, mutant PNPLA3 overexpression prevented NF-kB inhibitor-induced down-regulation of TNF-alpha expression in PA-treated HepG2 cells. Palmitic Acid tumor necrosis factor Homo sapiens