Pub. Date : 2019
PMID : 31787877
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Region-Specific Reduction of BDNF Protein and Transcripts in the Hippocampus of Juvenile Rats Prenatally Treated With Sodium Valproate. | Valproic Acid | brain-derived neurotrophic factor | Rattus norvegicus |
| 2 | In situ hybridization (ISH) experiments revealed that Valproate reduced BDNF mRNA, especially long-3"UTR-containing transcripts, in specific areas of the dentate gyrus (DG) and CA3 regions. | Valproic Acid | brain-derived neurotrophic factor | Rattus norvegicus |
| 3 | At the same time, Valproate reduced BDNF immunoreactivity in the suprapyramidal and lucidum layers of CA3, but improved hippocampus-dependent spatial learning. | Valproic Acid | brain-derived neurotrophic factor | Rattus norvegicus |