Title : ROS-induced NLRP3 inflammasome priming and activation mediate PCB 118- induced pyroptosis in endothelial cells.

Pub. Date : 2020 Feb

PMID : 31785945






2 Functional Relationships(s)
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1 The ROS scavenger (+-)-alpha-tocopherol and the NFkappaB inhibitor BAY11-7082 reversed the upregulation of NLRP3 expression and the increase in NLRP3 inflammasome activation induced by PCB 118 exposure in HUVECs. 3-(4-methylphenylsulfonyl)-2-propenenitrile NLR family pyrin domain containing 3 Homo sapiens
2 The ROS scavenger (+-)-alpha-tocopherol and the NFkappaB inhibitor BAY11-7082 reversed the upregulation of NLRP3 expression and the increase in NLRP3 inflammasome activation induced by PCB 118 exposure in HUVECs. 3-(4-methylphenylsulfonyl)-2-propenenitrile NLR family pyrin domain containing 3 Homo sapiens