Pub. Date : 2020 Feb 12
PMID : 31785814
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interestingly, the combination treatment of VPA and anti-PD-L1 antibody activated IRF1/IRF8 transcriptional axis in MDSCs leading to blockade of their immunosuppressive function by downregulating the expression of IL-10, IL-6, and ARG1 while re-activating CD8+ T-cells for the production of TNFalpha to further enhance anti-tumor immunity. | Valproic Acid | interleukin 6 | Homo sapiens |