Pub. Date : 2019 Nov 29
PMID : 31783879
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway. | docosahexaenoylascorbic acid | forkhead box C1 | Mus musculus |
2 | In vivo, endogenous DHA by the mfat-1 transgene enhanced miR-138-5p expression and decreased FOXC1 expression. | docosahexaenoylascorbic acid | forkhead box C1 | Mus musculus |
3 | CONCLUSIONS: These data identified the RvD1/miR-138-5p/FOXC1 pathway as a novel mechanism by DHA and its metabolite, RvD1, and the potential of targeting such pathway as a therapeutic strategy in treating NSCLC. | docosahexaenoylascorbic acid | forkhead box C1 | Mus musculus |