Title : Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway.

Pub. Date : 2019 Nov 29

PMID : 31783879






3 Functional Relationships(s)
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1 Inhibition of lung cancer growth and metastasis by DHA and its metabolite, RvD1, through miR-138-5p/FOXC1 pathway. docosahexaenoylascorbic acid forkhead box C1 Mus musculus
2 In vivo, endogenous DHA by the mfat-1 transgene enhanced miR-138-5p expression and decreased FOXC1 expression. docosahexaenoylascorbic acid forkhead box C1 Mus musculus
3 CONCLUSIONS: These data identified the RvD1/miR-138-5p/FOXC1 pathway as a novel mechanism by DHA and its metabolite, RvD1, and the potential of targeting such pathway as a therapeutic strategy in treating NSCLC. docosahexaenoylascorbic acid forkhead box C1 Mus musculus