Title : Investigation of Modulatory Effect of Pinolenic Acid (PNA) on Inflammatory Responses in Human THP-1 Macrophage-Like Cell and Mouse Models.

Pub. Date : 2020 Apr

PMID : 31776889






1 Functional Relationships(s)
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1 Topical application of PNA or Delta7-ETrA on mouse back skin suppressed TPA-induced pro-inflammatory mediator production, including IL-1beta, IL-6, TNF-alpha, and PGE2, as well as the phosphorylation of p38- and JNK-mitogen-activated protein kinase (MAPK), but not that of ERK-MAPK. 5,9,12-octadecatrienoic acid interleukin 1 beta Mus musculus