Title : Structural Basis of Catalysis and Inhibition of HDAC6 CD1, the Enigmatic Catalytic Domain of Histone Deacetylase 6.

Pub. Date : 2019 Dec 10

PMID : 31755702






2 Functional Relationships(s)
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1 Catalytic activity measurements with HDAC6 CD1 confirm the preference for peptide substrates containing C-terminal acetyllysine residues. N-epsilon-Acetyl-L-lysine CD1c molecule Homo sapiens
2 However, these measurements also show that CD1 exhibits weak activity for peptide substrates bearing certain small amino acids on the carboxyl side of the scissile acetyllysine residue. N-epsilon-Acetyl-L-lysine CD1c molecule Homo sapiens