Title : Synovium stem cell-derived matrix enhances anti-inflammatory properties of rabbit articular chondrocytes via the SIRT1 pathway.

Pub. Date : 2020 Jan

PMID : 31753397






1 Functional Relationships(s)
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1 Furthermore, we found that SIRT1 inhibition by nicotinamide completely counteracted the protective effect of DECM on chondrocytes in the presence of IL-1beta or TNF-alpha, indicating that the SIRT1 signaling pathway was involved in the DECM-mediated enhancement of anti-inflammatory properties of chondrocytes. Niacinamide tumor necrosis factor Homo sapiens