Title : Acetylshikonin Sensitizes Hepatocellular Carcinoma Cells to Apoptosis through ROS-Mediated Caspase Activation.

Pub. Date : 2019 Nov 19

PMID : 31752383






2 Functional Relationships(s)
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1 Thus, the current study intends to discover novel shikonin derivatives which can sensitize the liver cancer cell to TRAIL-induced apoptosis while exhibiting little toxicity toward the normal hepatic cell. shikonin TNF superfamily member 10 Homo sapiens
2 Herein, we demonstrated that non-cytotoxic doses of acetylshikonin (ASH), one of the shikonin derivatives, in combination with TRAIL, could promote apoptosis in HepG2 cells. shikonin TNF superfamily member 10 Homo sapiens