Pub. Date : 2019 Nov 18
PMID : 31752145
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In cancer cells, CN induced apoptosis and cell cycle arrest at G2/M phase through a p53-mediated mechanism, where p53 was activated, p21 and pro-apoptotic proteins Bid and Bak were upregulated, and PARP was cleaved. | Curcumin | H3 histone pseudogene 16 | Homo sapiens |
| 2 | In non-transformed human mammary epithelial cells MCF10A, CN at 50 microM had no cytotoxicity and p53 was not activated, but curcumin at 12.5 microM activated p53 and p21 and inhibited MCF10A cell growth. | Curcumin | H3 histone pseudogene 16 | Homo sapiens |