Title : All-trans-retinoic acid generation is an antidotal clearance pathway for all-trans-retinal in the retina.

Pub. Date : 2019 Dec.

PMID : 31749343






1 Functional Relationships(s)
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1 Moreover, we found that mRNA expression of retinoic acid-specific hydroxylase CYP26b1 was dose-dependently up-regulated by atRal exposure in RPE cells, indicating that atRA inactivation may be also initiated in atRal-accumulated RPE cells. Tretinoin cytochrome P450, family 26, subfamily b, polypeptide 1 Mus musculus