Pub. Date : 2020 Jan
PMID : 31746387
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present study examined whether lipoxin A4 (LXA4) increases the expression of HO-1, and inhibits the production of interleukin 6 (IL-6) and monocyte chemotactic protein 1 (MCP-1) in LXA4-induced protection during hyperoxia-induced injury in murine lung epithelial cells (MLE-12) and what signal pathway may participate in the actions of LXA4 inhibiting IL-6 and MCP-1. | lipoxin A4 | interleukin 6 | Mus musculus |
| 2 | The present study examined whether lipoxin A4 (LXA4) increases the expression of HO-1, and inhibits the production of interleukin 6 (IL-6) and monocyte chemotactic protein 1 (MCP-1) in LXA4-induced protection during hyperoxia-induced injury in murine lung epithelial cells (MLE-12) and what signal pathway may participate in the actions of LXA4 inhibiting IL-6 and MCP-1. | lipoxin A4 | interleukin 6 | Mus musculus |
| 3 | The present study examined whether lipoxin A4 (LXA4) increases the expression of HO-1, and inhibits the production of interleukin 6 (IL-6) and monocyte chemotactic protein 1 (MCP-1) in LXA4-induced protection during hyperoxia-induced injury in murine lung epithelial cells (MLE-12) and what signal pathway may participate in the actions of LXA4 inhibiting IL-6 and MCP-1. | lipoxin A4 | interleukin 6 | Mus musculus |
| 4 | The present study examined whether lipoxin A4 (LXA4) increases the expression of HO-1, and inhibits the production of interleukin 6 (IL-6) and monocyte chemotactic protein 1 (MCP-1) in LXA4-induced protection during hyperoxia-induced injury in murine lung epithelial cells (MLE-12) and what signal pathway may participate in the actions of LXA4 inhibiting IL-6 and MCP-1. | lipoxin A4 | interleukin 6 | Mus musculus |
| 5 | The present study examined whether lipoxin A4 (LXA4) increases the expression of HO-1, and inhibits the production of interleukin 6 (IL-6) and monocyte chemotactic protein 1 (MCP-1) in LXA4-induced protection during hyperoxia-induced injury in murine lung epithelial cells (MLE-12) and what signal pathway may participate in the actions of LXA4 inhibiting IL-6 and MCP-1. | lipoxin A4 | interleukin 6 | Mus musculus |
| 6 | The present study examined whether lipoxin A4 (LXA4) increases the expression of HO-1, and inhibits the production of interleukin 6 (IL-6) and monocyte chemotactic protein 1 (MCP-1) in LXA4-induced protection during hyperoxia-induced injury in murine lung epithelial cells (MLE-12) and what signal pathway may participate in the actions of LXA4 inhibiting IL-6 and MCP-1. | lipoxin A4 | interleukin 6 | Mus musculus |
| 7 | LXA4 significantly increased the cell survival rates, cell viability, SOD levels and HO-1 expression, reduced the apoptosis rates, and inhibited the MCP-1 and IL-6 levels induced by hyperoxia in cells. | lipoxin A4 | interleukin 6 | Mus musculus |
| 8 | The protection of LXA4 in hyperoxia-induced cell injury may be associated with the downregulation IL-6 and MCP-1 levels via the inhibition of the p38 MAPK and ERK1/2 signaling pathways. | lipoxin A4 | interleukin 6 | Mus musculus |