Pub. Date : 2020 Jan
PMID : 31746077
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lactate-fueled Oxidative Metabolism Drives DNMT1-mediated TAZ Activation. | Lactic Acid | tafazzin, phospholipid-lysophospholipid transacylase | Homo sapiens |
| 2 | Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells. | Lactic Acid | tafazzin, phospholipid-lysophospholipid transacylase | Homo sapiens |
| 3 | Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells. | Lactic Acid | tafazzin, phospholipid-lysophospholipid transacylase | Homo sapiens |
| 4 | Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells. | Lactic Acid | tafazzin, phospholipid-lysophospholipid transacylase | Homo sapiens |
| 5 | Here we investigated the role of lactate in regulation of activity of TAZ and showed glycolysis-derived lactate efficiently increased TAZ expression and activity in lung cancer cells. | Lactic Acid | tafazzin, phospholipid-lysophospholipid transacylase | Homo sapiens |
| 6 | Upregulation of DNMT1 by lactate caused hypermethylation of TAZ negative regulator of LATS2 gene promoter, leading to TAZ activation. | Lactic Acid | tafazzin, phospholipid-lysophospholipid transacylase | Homo sapiens |
| 7 | Upregulation of DNMT1 by lactate caused hypermethylation of TAZ negative regulator of LATS2 gene promoter, leading to TAZ activation. | Lactic Acid | tafazzin, phospholipid-lysophospholipid transacylase | Homo sapiens |