Title : Differential Nicotinic Modulation of Glutamatergic and GABAergic VTA Microcircuits.

Pub. Date : 2019 Nov/Dec

PMID : 31744841






1 Functional Relationships(s)
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1 These actions of nicotine, which occurred at concentrations of nicotine found in the artificial cerebrospinal fluid of cigarette smokers, may play a role in the reward system"s adaptive response to repeated nicotine exposure.Significance Statement This study uncovers novel aspects of nAChR neuropharmacology and VTA neurobiology that have implications for understanding nicotine dependence mechanisms. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus