Title : Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A.

Pub. Date : 2019

PMID : 31736764






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Since tyramine is a prototypic substrate of monoamine oxidase A (MAO-A), genetic polymorphisms in MAO-A may also be relevant. Tyramine monoamine oxidase A Homo sapiens
2 Since tyramine is a prototypic substrate of monoamine oxidase A (MAO-A), genetic polymorphisms in MAO-A may also be relevant. Tyramine monoamine oxidase A Homo sapiens
3 Since tyramine is a prototypic substrate of monoamine oxidase A (MAO-A), genetic polymorphisms in MAO-A may also be relevant. Tyramine monoamine oxidase A Homo sapiens
4 The aims of this study were to identify to what extent the interindividual variation in pharmacokinetics and pharmacodynamics of tyramine is determined by genetic polymorphisms in OCT1, CYP2D6, and MAO-A. Tyramine monoamine oxidase A Homo sapiens
5 Beyond that, we wanted to evaluate tyramine as probe drug for the in vivo activity of MAO-A and OCT1. Tyramine monoamine oxidase A Homo sapiens