Title : Effects of vitamin D on steroidogenesis, reactive oxygen species production, and enzymatic antioxidant defense in human granulosa cells of normal and polycystic ovaries.

Pub. Date : 2020 Mar

PMID : 31705961






4 Functional Relationships(s)
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1 Vit.D significantly increased aromatase and 3beta-hydroxysteroid dehydrogenase activity in N-GCs and PCO-GCs. Nitrogen vitrin Homo sapiens
2 Basal ROS in PCO-GCs was markedly greater than that of N-GCs, which was attenuated by vit.D treatment. Nitrogen vitrin Homo sapiens
3 We conclude that vit.D improved N-GCs and PCO-GCs functions through affecting steroidogenesis and enzymatic antioxidant defense. Nitrogen vitrin Homo sapiens
4 Under vit.D treatment, PCO-GCs could act more similar to N-GCs. Nitrogen vitrin Homo sapiens