Title : The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice.

Pub. Date : 2020 Feb 3

PMID : 31697983






1 Functional Relationships(s)
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1 Furthermore, ACT001 abolished MPTP-induced alpha-synuclein overexpression, astrocyte activation and interleukin-1beta (IL-1beta) production in the substantia nigra and striatum of the mouse brain. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine interleukin 1 beta Mus musculus