Title : Solution equilibrium, structural and cytotoxicity studies on Ru(η6-p-cymene) and copper complexes of pyrazolyl thiosemicarbazones.

Pub. Date : 2020 Jan

PMID : 31689626






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Me-pyrTSC and Ph-pyrTSC exhibited moderate cytotoxicity against human colonic adenocarcinoma cell lines (IC50 = 33-76 muM), while their complexation with Ru(eta6-p-cymene) (IC50 = 11-24 muM) and especially Cu(II) (IC50 = 3-6 muM) resulted in higher cytotoxicity. 4-cymene latexin Homo sapiens
2 Me-pyrTSC and Ph-pyrTSC exhibited moderate cytotoxicity against human colonic adenocarcinoma cell lines (IC50 = 33-76 muM), while their complexation with Ru(eta6-p-cymene) (IC50 = 11-24 muM) and especially Cu(II) (IC50 = 3-6 muM) resulted in higher cytotoxicity. 4-cymene latexin Homo sapiens