Title : Pueraria lobata and Daidzein Reduce Cytotoxicity by Enhancing Ubiquitin-Proteasome System Function in SCA3-iPSC-Derived Neurons.

Pub. Date : 2019

PMID : 31687087






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The expanded CAG repeats encode a polyglutamine (polyQ) tract at the C-terminus of the ATXN3 protein. polyglutamine ataxin 3 Homo sapiens
2 ATXN3 containing expanded polyQ forms aggregates, leading to subsequent cellular dysfunctions including an impaired ubiquitin-proteasome system (UPS). polyglutamine ataxin 3 Homo sapiens