Title : Protective Effect and Mechanism of Boswellic Acid and Myrrha Sesquiterpenes with Different Proportions of Compatibility on Neuroinflammation by LPS-Induced BV2 Cells Combined with Network Pharmacology.

Pub. Date : 2019 Oct 31

PMID : 31683684






2 Functional Relationships(s)
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1 The data showed that the different ratios of BA and MS had different degrees of inhibition of interleukin-1beta (IL-1beta), IL-6, and inducible nitric oxide synthase (iNOS) mRNA expression, down-regulated the phosphor-nuclear factor kappa B/nuclear factor kappa B (p-NF-kB)/(NF-kB), phosphorylated protein kinase b/protein kinase b (p-AKT/AKT), and Toll-like receptor 4 (TLR4) protein expression levels, and increased phospho-PI3 kinase (p-PI3K) protein expression levels. boswellic acid interleukin 1 beta Mus musculus
2 The data showed that the different ratios of BA and MS had different degrees of inhibition of interleukin-1beta (IL-1beta), IL-6, and inducible nitric oxide synthase (iNOS) mRNA expression, down-regulated the phosphor-nuclear factor kappa B/nuclear factor kappa B (p-NF-kB)/(NF-kB), phosphorylated protein kinase b/protein kinase b (p-AKT/AKT), and Toll-like receptor 4 (TLR4) protein expression levels, and increased phospho-PI3 kinase (p-PI3K) protein expression levels. boswellic acid interleukin 1 beta Mus musculus