Pub. Date : 2019 Oct
PMID : 31681485
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Vitamin D maintains E-cadherin intercellular junctions by downregulating MMP-9 production in human gingival keratinocytes treated by TNF-alpha. | Vitamin D | tumor necrosis factor | Homo sapiens |
| 2 | Vitamin D reduced the production of MMP-9 and attenuated the breakdown of ECJs in the HGKs treated with TNF-alpha. | Vitamin D | tumor necrosis factor | Homo sapiens |
| 3 | In addition, vitamin D downregulated TNF-alpha-induced nuclear factor kappa B (NF-kappaB) signaling in the HGKs. | Vitamin D | tumor necrosis factor | Homo sapiens |
| 4 | Conclusions: These results suggest that vitamin D may avert TNF-alpha-induced downregulation of the development of ECJs in HGKs by decreasing the production of MMP-9, which was upregulated by TNF-alpha. | Vitamin D | tumor necrosis factor | Homo sapiens |
| 5 | Conclusions: These results suggest that vitamin D may avert TNF-alpha-induced downregulation of the development of ECJs in HGKs by decreasing the production of MMP-9, which was upregulated by TNF-alpha. | Vitamin D | tumor necrosis factor | Homo sapiens |
| 6 | Vitamin D may reinforce ECJs by downregulating NF-kappaB signaling, which is upregulated by TNF-alpha. | Vitamin D | tumor necrosis factor | Homo sapiens |