Title : KMS99220 Exerts Anti-Inflammatory Effects, Activates the Nrf2 Signaling and Interferes with IKK, JNK and p38 MAPK via HO-1.

Pub. Date : 2019 Oct 31

PMID : 31656063






1 Functional Relationships(s)
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1 In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice, oral administration of KMS99220 attenuated microglial activation and decreased the levels of inducible nitric oxide synthase and interleukin 1 beta (IL-1b) in the nigrostriatal system. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine interleukin 1 beta Mus musculus