Title : COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.

Pub. Date : 2020 Apr

PMID : 31646730






1 Functional Relationships(s)
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1 We found that PTUPB alleviated the pathological changes of lung tissue and collagen deposition, as well as reduced senescence marker molecules (p16Ink4a and p53-p21Waf1/Cip1 ) in the lungs of mice treated by BLM. Bleomycin cyclin-dependent kinase inhibitor 1A (P21) Mus musculus