Pub. Date : 2019
PMID : 31632492
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Rsv enhanced the sensitivity of K562/RA cells to ATO and reduced the required dose of ATO as well as associated adverse reactions by promoting the proliferation inhibitory and apoptosis-inducing effects of ATO, which may be associated with reduced expression of the drug resistance genes mdr1/P-gp, mrp1/MRP1 and bcrp/BCRP, as well as the apoptotic inhibitory genes bcl-2, NF-kappaB and P53, and conversely, activation of caspase-3. | resveratrol | ATP binding cassette subfamily B member 1 | Homo sapiens |