Title : Enantioselective Radical Construction of 5-Membered Cyclic Sulfonamides by Metalloradical C-H Amination.

Pub. Date : 2019 Nov 13

PMID : 31622088






1 Functional Relationships(s)
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1 In addition to C-H bonds with varied electronic properties, the Co(II)-based metalloradical system features chemoselective amination of allylic C-H bonds and is compatible with heteroaryl groups, producing functionalized 5-membered chiral cyclic sulfonamides in high yields with high enantioselectivities. Sulfonamides mitochondrially encoded cytochrome c oxidase II Homo sapiens