Title : Thrombin Upregulates PAI-1 and Mesothelial-Mesenchymal Transition Through PAR-1 and Contributes to Tuberculous Pleural Fibrosis.

Pub. Date : 2019 Oct 13

PMID : 31614900






1 Functional Relationships(s)
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1 In carbon black/bleomycin-treated mice, knockdown of protease-activated receptor-1 (PAR-1) markedly downregulated alpha-smooth muscle actin (alpha-SMA) and fibronectin, and attenuated pleural fibrosis. Bleomycin actin alpha 2, smooth muscle, aorta Mus musculus