Title : PD-L1 expression levels on tumor cells affect their immunosuppressive activity.

Pub. Date : 2019 Nov

PMID : 31612048






1 Functional Relationships(s)
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1 Additionally, it was demonstrated that the tumor cells with higher levels of PD-L1 expression suppressed signaling pathways involved in T-cell activation, such as the T-cell receptor- zeta chain of T cell receptor associated protein kinase ZAP70-RAS-GTPase-extracellular-signal-regulated kinases and CD28-PI3K-Akt serine/threonine kinases pathways. glycyl-threonine zeta chain of T cell receptor associated protein kinase 70 Homo sapiens