Title : β-blockers augment L-type Ca2+ channel activity by targeting spatially restricted β2AR signaling in neurons.

Pub. Date : 2019 Oct 14

PMID : 31609201






1 Functional Relationships(s)
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1 The cAMP/PKA activities are restricted within the immediate vicinity of activated beta2AR, leading to selectively enhance PKA-dependent phosphorylation and stimulation of endogenous L-type calcium channel (LTCC) but not AMPA receptor in rat hippocampal neurons. alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid adrenergic receptor, beta 2 Mus musculus